The School of Nursing was added to the curriculum at SFA in 1977. The first students admitted to the program were registered nurses with associate degrees who were seeking a bachelors degree. It was not until fall of 1981 when students were allowed to enter the program that had no background in the nursing.
In 2007 the Texas legislature passed a bill to authorize a new nursing school for SFA. The $13 million facility was built on 17 acres of land donated by Lucille and Richard, her late husband, DeWitt. A groundbreaking ceremony took place in January 2009 and opened in the spring of 2010.
As of March 2011 the Richard and Lucille Dewitt School of Nursing was part of the College of Sciences and Mathematics.